Certificate of Analysis
| Product Name: | Cobimetinib hemifumarate |
| Catalog Number: | M14168 |
| CAS Number: | 1369665-02-0 |
Physical and Chemical Properties
| Molecular Weight: | 589.25 |
| Solubility: | DMSO 50 mg/mL |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM. In addition, Cobimetinib is an inhibitor of Akt. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |