Certificate of Analysis
| Product Name: | CHIR-99021 HCl |
| Catalog Number: | M1989 |
| CAS Number: | 1797989-42-4 |
Physical and Chemical Properties
| Formula: | C22H18Cl2N8.HCl |
| Molecular Weight: | 501.8 |
| Solubility: | DMSO 35 mg/mL; Water 6 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.05% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | CHIR-99021 HCl (Laduviglusib; CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |