Certificate of Analysis

 

Product Name: CHIR-99021 HCl
Catalog Number: M1989
CAS Number: 1797989-42-4

Physical and Chemical Properties
Formula: C22H18Cl2N8.HCl
Molecular Weight: 501.8
Solubility: DMSO 60 mg/mL; Water 6 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: CHIR-99021 HCl Structure
Analytical Data
QC Standard: 99.05%
H-NMR: Consistent with structure
Product Information
Description: CHIR-99021 HCl (CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.