Certificate of Analysis

 

Product Name: Tucidinostat (Chidamide)
Catalog Number: M6178
CAS Number: 1616493-44-7

Physical and Chemical Properties
Formula: C22H19FN4O2
Molecular Weight: 390.41
Solubility: DMSO 50 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Tucidinostat (Chidamide) Structure
Analytical Data
QC Standard: 98.06%
H-NMR: Consistent with structure
Product Information
Description: Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.