Certificate of Analysis

 
Product Name: CGP 60474
Catalog Number: M6589
CAS Number: 164658-13-3
Physical and Chemical Properties
Formula: C18H18ClN5O
Molecular Weight: 355.82
Form: Solid
Solubility: DMSO ≥ 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: CGP 60474 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: CGP60474 is a highly effective anti-endotoxin drug, It is an effective cyclin-dependent kinase (CDK) inhibitor (IC50 of CDK1/B, CDK2/E, CDK2/ A, CDK4/D, CDK5/ P25, CDK7/H and CDK9/T are 26, 3, 4, 216, 10, 200 and 13 nM, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.