Certificate of Analysis

 

Product Name: Cemdisiran, terminal sugar modification- 
Catalog Number: M28435
CAS Number: 1436858-07-9

Physical and Chemical Properties
Formula: C78H140N11O34P
Molecular Weight: 1806.97
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: Cemdisiran, terminal sugar modification-  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Cemdisiran, terminal sugar modification- is an investigational N-acetylgalactosamine-conjugated RNAi agent. Cemdisiran, a siRNA-targeting C5 mRNA, suppresses liver production of complement component C5.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.