Certificate of Analysis
| Product Name: | CD532 hydrochloride |
| Catalog Number: | M31003 |
Physical and Chemical Properties
| Formula: | C26H26ClF3N8O |
| Molecular Weight: | 558.99 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | 4°C, dry, sealed |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride also can directly interact with AURKA and induces a global conformational shift. CD532 hydrochloride can be used for the research of cancer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |