Certificate of Analysis
| Product Name: | Casein Kinase inhibitor A86 |
| Catalog Number: | M45288 |
| CAS Number: | 2079069-01-3 |
Physical and Chemical Properties
| Formula: | C18H25FN6 |
| Molecular Weight: | 344.43 |
| Form: | Solid |
| Solubility: | DMSO 12.5 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Casein Kinase inhibitor A86 is a potent and orally active casein kinase 1α (CK1α) inhibitor that also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb). In addition, Casein Kinase inhibitor A86 induces apoptosis in leukemia cells and may be used in leukemia-related studies. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |