Certificate of Analysis
| Product Name: | BTX161 |
| Catalog Number: | M45283 |
| CAS Number: | 2052301-24-1 |
Physical and Chemical Properties
| Formula: | C15H16N2O3 |
| Molecular Weight: | 272.30 |
| Form: | Solid |
| Solubility: | DMSO 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BTX161 is a Thalidomide analog and potent CKIα degrader.BTX161 mediates the degradation of CKIα better than Lenalidomide and activates the DNA damage response (DDR) and p53 while stabilizing the p53 antagonist MDM2 in human AML cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |