Certificate of Analysis

 

Product Name: BRM/BRG1 ATP Inhibitor-1
Catalog Number: M10668
CAS Number: 2270879-17-7

Physical and Chemical Properties
Formula: C11H9F3N4O2S
Molecular Weight: 318.27
Solubility: DMSO ≥ 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: BRM/BRG1 ATP Inhibitor-1 Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: BRM/BRG1 ATP Inhibitor-1 is an orally active inhibitor (IC50 below 5 nM) of Brahma Homolog (BRM)​/SMARCA2 ATPase activity for the treatment of Brahma Related Gene 1 (BRG1)​/SMARCA4-​Mutant cancers.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.