Certificate of Analysis

 

Product Name: Brilaroxazine
Catalog Number: M28018
CAS Number: 1239729-06-6

Physical and Chemical Properties
Formula: C22H25Cl2N3O3
Molecular Weight: 450.36
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, protect from light
Chemical Structure: Brilaroxazine Structure
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki=1.5 nM) and 5-HT2A (Ki=2.5 nM), and has antagonist activity at 5-HT2B (Ki=0.19 nM), and 5-HT7 (Ki=2.7 nM) receptors.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.