Certificate of Analysis

 

Product Name: Brentuximab vedotin
Catalog Number: M25284
CAS Number: 914088-09-8

Physical and Chemical Properties
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: Brentuximab vedotin (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). Brentuximab vedotin inhibits CD30-positive cells with an IC50 of 2.5 ng/mL. Brentuximab vedotin can be used for the research of relapsed and refractory Hodgkin lymphoma.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.