Certificate of Analysis
| Product Name: | BRD4 degrader AT1 |
| Catalog Number: | M29228 |
| CAS Number: | 2098836-45-2 |
Physical and Chemical Properties
| Formula: | C48H58ClN9O5S3 |
| Molecular Weight: | 972.68 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |