Certificate of Analysis

 

Product Name: BOS-318 
Catalog Number: M29588
CAS Number: 2387633-15-8

Physical and Chemical Properties
Formula: C28H32Cl2N6O3
Molecular Weight: 571.5
Form: Solid
Solubility: DMSO 50 mg/mL (ultrasonic)
Storage: Powder -20°C
Chemical Structure: BOS-318  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.