Certificate of Analysis
| Product Name: | BMS-8 |
| Catalog Number: | M28797 |
| CAS Number: | 1675201-90-7 |
Physical and Chemical Properties
| Formula: | C27H28BrNO3 |
| Molecular Weight: | 494.42 |
| Form: | Solid |
| Solubility: | DMSO 83.33 mg/mL (ultrasonic) |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |