Certificate of Analysis
| Product Name: | BMS-688521 |
| Catalog Number: | M30828 |
| CAS Number: | 893397-44-9 |
Physical and Chemical Properties
| Formula: | C26H19Cl2N5O4 |
| Molecular Weight: | 536.37 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BMS-688521 is a highly potent, orally active inhibitor of the LFA-1/ICAM interaction, with an IC50 of 2.5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay. BMS-688521 is efficacious in a mouse allergic eosinophilic lung inflammation model. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |