Certificate of Analysis

 

Product Name: Talazoparib (BMN-673)
Catalog Number: M1732
CAS Number: 1207456-01-6

Physical and Chemical Properties
Formula: C19H14F2N6O
Molecular Weight: 380.35
Solubility: DMSO 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Talazoparib (BMN-673) Structure
Analytical Data
QC Standard: 99.86%
H-NMR: Consistent with structure
Product Information
Description: Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.