Certificate of Analysis
| Product Name: | BLZ945 (Sotuletinib) |
| Catalog Number: | M5316 |
| CAS Number: | 953769-46-5 |
Physical and Chemical Properties
| Formula: | C20H22N4O3S |
| Molecular Weight: | 398.48 |
| Solubility: | DMSO 69 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.88% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Sotuletinib (BLZ945) is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |