Certificate of Analysis


Catalog Number: M9801
Product Name: BI-3406
CAS Number: 2230836-55-0

Physical and Chemical Properties
Formula: C23H25F3N4O3
Molecular Weight: 462.46
Solubility: DMSO ≥ 90 mg/mL
Storage: 2-8°C, dry, protect from light, sealed
Chemical Structure: BI-3406 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: BI-3406 is a highly potent and selective SOS1::KRAS inhibitor (IC50=6 nM), which selectively binds to SOS1 and blocks the interaction with KRAS, irrespective of the KRAS mutation.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.