Certificate of Analysis

 

Product Name: Nerandomilast (BI 1015550)
Catalog Number: M25404
CAS Number: 1423719-30-5

Physical and Chemical Properties
Formula: C20H25ClN6O2S
Molecular Weight: 448.97
Solubility: DMSO 6 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Nerandomilast (BI 1015550) Structure
Analytical Data
QC Standard: >99.5%
H-NMR: Consistent with structure
Product Information
Description: Nerandomilast (BI 1015550) is a novel, orally active phosphodiesterase 4B (PDE4B) inhibitor (IC50 = 7.2 nM) with anti-fibrotic and anti-inflammatory effects.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.