Certificate of Analysis

 

Product Name: Bezuclastinib
Catalog Number: M28692
CAS Number: 1616385-51-3

Physical and Chemical Properties
Formula: C19H17N5O
Molecular Weight: 331.37
Form: Solid
Solubility: DMSO 75 mg/mL (ultrasonic)
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: Bezuclastinib Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Bezuclastinib (CGT9486; PLX 9486) is a potent inhibitor of c-kit and c-kit D816V (0.0001 < IC50 < 1 μM). Bezuclastinib is a tyrosine kinase inhibitor.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.