Certificate of Analysis
| Product Name: | BEZ235 |
| Catalog Number: | M1671 |
| CAS Number: | 915019-65-7 |
Physical and Chemical Properties
| Formula: | C30H23N5O |
| Molecular Weight: | 469.55 |
| Solubility: | DMSO 3 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.62% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BEZ235 (NVP-BEZ235) is a potent dual PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |