Certificate of Analysis
| Product Name: | BETd-246 |
| Catalog Number: | M10792 |
| CAS Number: | 2140289-17-2 |
Physical and Chemical Properties
| Formula: | C48H55N11O10 |
| Molecular Weight: | 946.02 |
| Solubility: | DMSO ≥ 150 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BETd-246 is a second-generation, PROTAC-based, BET bromine terminal domain (BRD) inhibitor that is connected by Cereblon ligands and BET ligands with good selectivity, efficacy and antitumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |