Certificate of Analysis
| Product Name: | BDE-47 |
| Catalog Number: | M55229 |
| CAS Number: | 5436-43-1 |
Physical and Chemical Properties
| Formula: | C12H6Br4O |
| Molecular Weight: | 485.79 |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥97.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BDE-47 is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation. BDE-47 reduced cell viability and disrupted mitochondrial dynamics by inhibiting mitochondrial fusion and fission simultaneously, leading to MMP decreases, ROS overgeneration, ATP depletion, and cellular disintegration in a dose-dependent manner. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |