Certificate of Analysis
| Product Name: | BAY-293 |
| Catalog Number: | M9359 |
| CAS Number: | 2244904-70-7 |
Physical and Chemical Properties
| Formula: | C25H28N4O2S |
| Molecular Weight: | 448.58 |
| Solubility: | DMSO ≥ 70 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.52% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BAY-293 is a potent inhibitor of Son of Sevenless 1 (SOS1), blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |