Certificate of Analysis

 

Catalog Number: M10491
Product Name: Batabulin sodium
CAS Number: 195533-98-3

Physical and Chemical Properties
Formula: C13H6F6NNaO3S
Molecular Weight: 393.24
Solubility: DMSO 100 mg/mL
Storage: at -20°C
Chemical Structure: Batabulin sodium Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Batabulin (T138067) sodium is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity, covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton, an increase in chromosomal ploidy, cell cycle arrest, and tumor cell apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.