Certificate of Analysis
| Product Name: | Balixafortide TFA |
| Catalog Number: | M31026 |
Physical and Chemical Properties
| Formula: | C86H119F3N24O23S2 |
| Molecular Weight: | 1978.16 |
| Form: | Solid |
| Solubility: | Water 100 mg/mL (ultrasonic); DMSO 100 mg/mL (ultrasonic) |
| Storage: | Store at ≤ -20°C, protect from light, dry, sealed |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide TFA is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |