Certificate of Analysis

 

Product Name: AZD5305
Catalog Number: M10298
CAS Number: 2589531-76-8

Physical and Chemical Properties
Formula: C22H26N6O2
Molecular Weight: 406.48
Solubility: DMSO 12 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AZD5305 Structure
Analytical Data
QC Standard: 99.60%
H-NMR: Consistent with structure
Product Information
Description: Saruparib (AZD5305) is a potent and oral active, second-generation PARP (highly selective PARP1) inhibitor with IC50 values of 3 nM and 1400 nM for PARP1 and PARP2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.