Certificate of Analysis

 

Product Name: AZD-8529 mesylate 
Catalog Number: M28165
CAS Number: 1314217-69-0

Physical and Chemical Properties
Formula: C25H28F3N5O6S
Molecular Weight: 583.58
Form: Solid
Solubility: DMSO 41.67 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: AZD-8529 mesylate  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.