Certificate of Analysis

 

Product Name: AZ13705339 
Catalog Number: M29109
CAS Number: 2016806-57-6

Physical and Chemical Properties
Formula: C33H36FN7O3S
Molecular Weight: 629.75
Form: Solid
Solubility: DMSO 250 mg/mL (ultrasonic)
Storage: Powder -20°C
Chemical Structure: AZ13705339  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.