Certificate of Analysis
| Product Name: | AZ 11645373 |
| Catalog Number: | M42215 |
| CAS Number: | 227088-94-0 |
Physical and Chemical Properties
| Formula: | C24H21N3O5S |
| Molecular Weight: | 463.51 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | |
| H-NMR: | Consistent with structure |
Product Information
| Description: | AZ11645373 is a highly selective and potent antagonist at human P2X7 receptors, AZ11645373 inhibits ATP-evoked IL-1β release from lps-activated THP-1 cells , with an IC50 value of 90 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |