Certificate of Analysis

 

Product Name: AX-024
Catalog Number: M13560
CAS Number: 1370544-73-2

Physical and Chemical Properties
Molecular Weight: 339.4
Solubility: Ethanol 90 mg/mL; DMSO 35 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AX-024 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.