Product Name: | AVG-233 |
Catalog Number: | M29304 |
CAS Number: | 2151937-80-1 |
Formula: | C26H22ClN5O3 |
Molecular Weight: | 487.94 |
Form: | Solid |
Solubility: | DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C) |
Storage: | 4°C, protect from light, dry, sealed |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC50=0.14-0.31 μM). AVG-233 can be used for research of respiratory syncytial virus (RSV). |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |