Certificate of Analysis

 

Product Name: AVG-233 
Catalog Number: M29304
CAS Number: 2151937-80-1

Physical and Chemical Properties
Formula: C26H22ClN5O3
Molecular Weight: 487.94
Form: Solid
Solubility: DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: AVG-233  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC50=0.14-0.31 μM). AVG-233 can be used for research of respiratory syncytial virus (RSV).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.