Certificate of Analysis
| Product Name: | ATX inhibitor 5 |
| Catalog Number: | M49398 |
| CAS Number: | 2402772-45-4 |
Physical and Chemical Properties
| Formula: | C22H18ClF3N6O |
| Molecular Weight: | 474.87 |
| Form: | Solid |
| Solubility: | DMSO >100 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ATX inhibitor 5 is a potent, orally active inhibitor of Autotaxin (ATX) with an IC50 of 15.3 nM.Additionally, AATX inhibitor 5 exhibits anti-hepatic fibrosis activity and significantly reduces CCl4-induced hepatic fibrosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |