Certificate of Analysis
| Product Name: | Atuzabrutinib |
| Catalog Number: | M28627 |
| CAS Number: | 1581714-49-9 |
Physical and Chemical Properties
| Formula: | C30H30FN7O2 |
| Molecular Weight: | 539.6 |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |