Certificate of Analysis
| Product Name: | AS-99 free base |
| Catalog Number: | M21504 |
| CAS Number: | 2323623-93-2 |
Physical and Chemical Properties
| Formula: | C27H30F3N5O3S2 |
| Molecular Weight: | 593.68 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | AS-99 is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |