Certificate of Analysis
| Product Name: | ARCC-4 |
| Catalog Number: | M10963 |
| CAS Number: | 1973403-00-7 |
Physical and Chemical Properties
| Formula: | C53H56F3N7O7S2 |
| Molecular Weight: | 1024.18 |
| Solubility: | DMSO ≥ 150 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ARCC-4 is based on PROTAC technology, a nanomolar grade androgen receptor (AR) degrader D50 The value is 5 nM. ARCC-4 is an AR PROTAC recruited by von Hippel-Lindau (VHL) based on enzalutamide. ARCC-4 effectively degrades AR mutations associated with antiandrogen studies. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |