Certificate of Analysis
| Product Name: | APY0201 |
| Catalog Number: | M8898 |
| CAS Number: | 1232221-74-7 |
Physical and Chemical Properties
| Formula: | C23H23N7O |
| Molecular Weight: | 413.48 |
| Form: | Solid |
| Solubility: | DMSO: ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | APY0201 is a potent and selective IL-12/23 inhibitor. APY0201 is also a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5.2 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |