Certificate of Analysis
| Product Name: | APR-246 (Eprenetapopt) |
| Catalog Number: | M9623 |
| CAS Number: | 5291-32-7 |
Physical and Chemical Properties
| Formula: | C10H17NO3 |
| Molecular Weight: | 199.25 |
| Solubility: | DMSO ≥ 60 mg/mL; Water ≥ 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.22% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | APR-246 (Eprenetapopt) is the first-in-class small molecule to restore wild-type p53 function in TP53 mutant cells. APR-246 (Eprenetapopt) also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of REDOX balance in cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |