Certificate of Analysis

 

Product Name: ALLO-2 
Catalog Number: M28238
CAS Number: 1357350-60-7

Physical and Chemical Properties
Formula: C18H12F3N5O
Molecular Weight: 371.32
Form: Solid
Solubility: DMSO 125 mg/mL (ultrasonic)
Storage: Powder -20°C
Chemical Structure: ALLO-2  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.