Certificate of Analysis
| Product Name: | RepSox (ALK5 Inhibitor II) |
| Catalog Number: | M1859 |
| CAS Number: | 446859-33-2 |
Physical and Chemical Properties
| Formula: | C17H13N5 |
| Molecular Weight: | 287.32 |
| Solubility: | DMSO ≥ 50 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | RepSox (ALK5 Inhibitor II) is a potent and ATP-competitive inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |