Certificate of Analysis
| Product Name: | Aficamten (CK-274) |
| Catalog Number: | M19970 |
| CAS Number: | 2364554-48-1 |
Physical and Chemical Properties
| Formula: | C18H19N5O2 |
| Molecular Weight: | 337.38 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Aficamten (CK-274, CK 3773274) is a novel cardiac myosin inhibitor that reduces myocardial contractile force in vitro and in vivo with an IC50 of 1.4 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |