Certificate of Analysis

 

Product Name: ACBI1
Catalog Number: M13389
CAS Number: 2375564-55-7

Physical and Chemical Properties
Formula: C49H58FN9O7S
Molecular Weight: 936.12
Solubility: DMSO ≥ 60 mg/mL
Storage: -20°C, protect from light, dry, sealed
Chemical Structure: ACBI1  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: ACBI1 is an effective and synergistic PROTAC inhibitor of SMARCA2, SMARCA4 and PBRM1, with DC50 of 6 nM, 11 nM and 32 nM in MV-4-11 cells, respectively. ACBI1 can induce antiproliferative effect and apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.