Certificate of Analysis
| Product Name: | Acalabrutinib |
| Catalog Number: | M5306 |
| CAS Number: | 1420477-60-6 |
Physical and Chemical Properties
| Formula: | C26H23N7O2 |
| Molecular Weight: | 465.51 |
| Solubility: | 80 mg/mL in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.21% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |