Certificate of Analysis
| Product Name: | Abemaciclib metabolite M18 hydrochloride |
| Catalog Number: | M13602 |
Physical and Chemical Properties
| Molecular Weight: | 531 |
| Solubility: | DMSO 90 mg/mL; Water 90 mg/mL |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
Product Information
| Description: | Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |