Certificate of Analysis
| Product Name: | Abemaciclib (LY2835219) |
| Catalog Number: | M10347 |
| CAS Number: | 1231929-97-7 |
Physical and Chemical Properties
| Formula: | C27H32F2N8 |
| Molecular Weight: | 506.59 |
| Solubility: | DMSO 3 mg/mL (ultrasonic and warming) |
| Storage: | 2-8°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Abemaciclib (LY2835219) is a best-in-class, selective and effective dual inhibitor of CDK4 and CDK6, which inhibits CDK4/CDK6 activity with IC50 of 2 nM and 10 nM respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |