Certificate of Analysis

 

Product Name: 6α-Hydroxy Paclitaxel
Catalog Number: M59073
CAS Number: 153212-75-0

Physical and Chemical Properties
Formula: C47H51NO15
Molecular Weight: 869.91
Form: Solid
Solubility: DMSO 5 mg/mL
Storage: Powder -20°C, sealed
Chemical Structure: 6α-Hydroxy Paclitaxel Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: 6α-Hydroxy Paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy Paclitaxel (6-Hydroxytaxol) retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.