Certificate of Analysis


Product Name: 3-TYP
Catalog Number: M8978
CAS Number: 120241-79-4

Physical and Chemical Properties
Formula: C7H6N4
Molecular Weight: 146.15
Solubility: DMSO ≥ 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: 3-TYP Structure
Analytical Data
HPLC: Shows Min 99.76% purity
H-NMR: Consistent with structure
Product Information
Description: 3-TYP is a selective SIRT3 inhibitor, more potent over SIRT1 and SIRT2, with IC50 values of 88 nM, 92 nM, 16 nM for SITR1, SIRT2, SIRT3, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.