Certificate of Analysis

 

Product Name: (2S,3R)-LP99 
Catalog Number: M28903
CAS Number: 1808948-28-8

Physical and Chemical Properties
Formula: C26H30ClN3O4S
Molecular Weight: 516.05
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: (2S,3R)-LP99  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: (2S,3R)-LP99 is a potent and selective BRD7 and BRD9 inhibitor with an KD of 99 nM for BRD9. (2S,3R)-LP99 inhibits the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. (2S,3R)-LP99 demonstrates that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.