Certificate of Analysis


Catalog Number: M1854
Product Name: VX-770
CAS Number: 873054-44-5

Physical and Chemical Properties
Formula: C24H28N2O3
Molecular Weight: 392.49
Solubility: DMSO ≥75 mg/mL
Long-term Storage: at -20°C
Chemical Structure: VX-770 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: VX-770 (Ivacaftor) is a potentiator of CFTR, which targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.