|Solubility:||DMSO ≥75 mg/mL|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min >99% purity|
|H-NMR:||Consistent with structure|
|Description:||VX-770 (Ivacaftor) is a potentiator of CFTR, which targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.