Certificate of Analysis

 

Product Name: VB124 
Catalog Number: M29388
CAS Number: 2230186-18-0

Physical and Chemical Properties
Formula: C23H23ClN2O4
Molecular Weight: 426.89
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: VB124  Structure
Analytical Data
QC Standard: 99.31%
H-NMR: Consistent with structure
Product Information
Description: VB124 is an orally active, potent, and selective MCT4 inhibitor. VB124 can specifically inhibit lactate efflux with IC50s of 8.6 nM and 19 nM for lactate import and export in MDA-MB-231 cells, respectively. VB124 is highly selective for MCT4 over MCT1. VB124 can be used for the research of cardiac hypertrophy, heart failure, and metabolism.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.